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Chapter1
ExecutiveSummary
ExecutiveSummary1-1
ExecutiveSummary1-1
Chapter2
TotalU.S.OpioidandNon-OpioidPainManagementPharmaceuticalsMarkets
MarketOverview2-1
Introduction2-1
ScopeandSegmentation2-2
ResearchMethodology2-3
Methodology2-4
BaseYearMarketAssumptions2-4
RestraintsinForecasts2-4
MarketEngineeringMeasurements2-4
MarketForecasts2-5
PatientForecasts2-5
PricingForecasts2-8
RevenueForecasts2-11
CompetitiveAnalysis2-13
MarketShareAnalysis2-13
ProductPipeline2-17
OpioidPainManagementPharmaceuticals2-17
Non-OpioidPainManagementPharmaceuticals2-18
Chapter3
U.S.OpioidPainManagementPharmaceuticalsMarket
MarketOverview3-1
Introduction3-1
MarketEngineeringMeasurements3-2
MarketAge3-3
Revenues3-3
PotentialRevenues3-3
BaseYearMarketGrowthRate3-3
CompoundAnnualGrowthRate3-3
Saturation3-4
AverageCostperPatient3-4
AverageCostperDay3-4
PriceSensitivity3-4
TotalPotentialPatients3-4
Competitors3-4
DegreeofCompetition3-5
DegreeofTechnicalChange3-5
MarketConcentration3-5
MarketForecasts3-5
PatientForecasts3-5
PricingForecasts3-7
RevenueForecasts3-10
CompetitiveAnalysis3-12
CompetitiveStructure3-12
MarketShareAnalysis3-13
Chapter4
U.S.Non-OpioidPainManagementPharmaceuticalsMarket
MarketOverview4-1
Introduction4-1
MarketEngineeringMeasurements4-2
MarketAge4-3
Revenues4-3
PotentialRevenues4-3
BaseYearMarketGrowthRate4-3
CompoundAnnualGrowthRate4-3
Saturation4-4
AverageCostperPatient4-4
AverageCostperDay4-4
PriceSensitivity4-4
TotalPotentialPatients4-4
Competitors4-4
DegreeofCompetition4-5
DegreeofTechnicalChange4-5
MarketForecasts4-5
PatientForecasts4-5
PricingForecasts4-7
RevenueForecasts4-9
CompetitiveAnalysis4-11
CompetitiveStructure4-11
MarketShareAnalysis4-12
Chapter5
DecisionSupportDatabases
DiseaseIncidence5-1
ArthritisPrevalence5-1
DemographicIndicators5-3
PopulationAbove655-3
PercentofPopulationAbove655-6
MalePopulationAbove655-8
FemalePopulationAbove655-11
MarketIndicator5-13
OTCasPercentofTotalPharma5-13
Pain is a universal human experience. The International Association for the Study of Pain (IASP) defines pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage. Pain may be a symptom of an underlying disease or disorder, or a disorder in its own right.
A pain message is transmitted to the central nervous system (CNS) by special peripheral nervous system (PNS) cells called nociceptors. These receptors are distributed throughout the body and respond to different stimuli depending on the location. For example, nociceptors that extend from the skin are stimulated by sensations such as pressure, temperature, and chemical changes. When a nociceptor is stimulated, neurotransmitters are released within the cell. Neurotransmitters are chemicals found within the nervous system that facilitate nerve cell communication. The nociceptor transmits its signal to nerve cells within the spinal cord, which conveys the pain message to the thalamus, a specific region in the brain.
